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The Lipedema Biohack 


Lipedema (sometimes called “lipoedema”, or more accurately “lipalgia”) is a chronic condition that causes an abnormal accumulation of painful adipose tissue (fat) in specific areas of the body (typically the legs).


Lipedema most often involves the buttocks, thighs and calves. The upper arms can also be affected. Lipedema is a condition that is almost exclusively found in women and women of any weight may develop lipedema. The fat associated with lipedema is resistant to traditional weight-loss methods. Over time mobility may be reduced, and due to reduced quality of life, patients often experience depression.


Other conditions that may present similarly include lipohypertrophy, chronic venous insufficiency, and lymphedema. It is estimated to affect up to 11% of women. Onset is typically during puberty, pregnancy, or menopause which is why hormones are believed to be involved.


Now, through Epigenetic Biohacking, you can take back control of your health! Science has now shown that every dis-ease known has a specific gene that isn't functioning at optimal range. It's not necessarily the blueprint passed down to you from your parents, rather, in 90% of cases, it's caused by some epigenetic factor such as pathogens, heavy metals, or toxins, for example. The good news is that, because of epigenetics, which is how your environment and lifestyle influence the expression of your genes, you can now reverse the negative expression of your genes through diet, lifestyle, and targeted supplementation thereby decreasing symptoms, and kick-starting the self-healing process.


This Biohack includes natural remedies for the main genes and pathways associated with Lipedema including the recommended summary protocol for them.

Lipedema Biohack Genes & Pathways:


  • AKR1C1 Gene - Aldo-Keto Reductase Family 1 Member C1
  • Synthesis of bile acids and bile salts SuperPath
  • CYP7B1 Gene - Cytochrome P450 Family 7 Subfamily B Member 1
  • Visual phototransduction SuperPath
  • RBP1 Gene - Retinol Binding Protein 1
  • Citric Acid Cycle
  • Steroidogenic Signaling Pathway
  • NR3C1 Gene - Nuclear Receptor Subfamily 3 Group C Member 1 (Glucocorticoid Receptor)
  • NR3C2 Gene - Nuclear Receptor Subfamily 3 Group C Member 2 (Mineralocorticoid Receptor)
  • HMGB1 Gene - High Mobility Group Box 1
  • HSP90AA1 Gene - Heat Shock Protein 90 Alpha Family Class A Member 1
  • CYP21A2 Gene - Cytochrome P450 Family 21 Subfamily A Member 2
  • Spinal cord injury Singleton SuperPath
  • PLA2G5 Gene - Phospholipase A2 Group V
  • Adipogenesis Singleton SuperPath
  • PCK1 Gene - Phosphoenolpyruvate Carboxykinase 1
  • LEP Gene – Leptin
  • IL6 Gene - Interleukin 6
  • PPARG Gene - Peroxisome Proliferator Activated Receptor Gamma
  • MIRLET7C Gene - MicroRNA Let-7c

Lipedema Biohack

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