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Now, through Epigenetic Biohacking, you can take back control of your health! Science has now shown that every dis-ease known has a specific gene that isn't functioning at optimal range. It's not necessarily the blueprint passed down to you from your parents, rather, in 90% of cases, it's caused by some epigenetic factor such as pathogens, heavy metals, or toxins, for example. The good news is that, because of epigenetics, which is how your environment and lifestyle influence the expression of your genes, you can now reverse the negative expression of your genes through diet, lifestyle, and targeted supplementation thereby decreasing symptoms, and kick-starting the self-healing process.


The Osteoarthritis Biohack is downloadable PDF file that's essentially a done-for-you remedy roadmap. We've done the research on the main genes and pathways involved with Osteoarthritis and show you exactly which natural compounds have the ability to modulate these genes and pathways back in your favor, thereby assisting the body in the reversal of symptoms and the dis-ease process itself.


Osteoarthritis is a common disease of the joints that primarily occurs in older adults. This condition is characterized by the breakdown of cartilage, the tough but flexible tissue that covers the ends of the bones at the joints and allows smooth joint movements. One or more parts of the body can be affected, most often the hands, shoulders, spine, knees, or hips.


Osteoarthritis usually develops slowly, causing pain, stiffness, and restricted movement as the condition gets worse. Areas of bone no longer cushioned by cartilage rub against each other and start to break down. Further damage is caused as the body attempts to repair and rebuild these tissues. The immune system, which plays a role in healing injuries, targets these areas, and its response leads to inflammation of the joint tissues.


People with osteoarthritis typically experience stiffness following periods of inactivity such as upon awakening or rising from a chair; the stiffness usually improves as they move around. In some affected individuals, the condition never causes major problems. In others, severe osteoarthritis can impair mobility and the ability to perform daily tasks, affecting quality of life and increasing the risk of other health conditions such as cardiovascular disease.

This Biohack includes natural remedies for the main genes and pathways associated with Osteoarthritis, including the recommended summary protocol.



  • HOTAIR Gene - HOX Transcript Antisense RNA
  • Vascular endothelial growth factor (VEGF)
  • Sirtuin 1 (SIRT1)
  • Wnt Signaling
  • SPP1 Gene - Secreted Phosphoprotein 1 (Osteopontin)
  • ECM Proteoglycans SuperPath
  • DCN Gene – Decorin
  • TGF-β/BMP Signaling
  • SMAD Genes - Mothers Against Decapentaplegic Homolog
  • Bone Morphogenetic Proteins
  • Extracellular Matrix Organization SuperPath
  • CAPN9 Gene - Calpain 9
  • MMP2 Gene - Matrix Metallopeptidase 2
  • GSK3B Gene - Glycogen Synthase Kinase 3 Beta
  • CHUK Gene - Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex
  • The Ubiquitin–Proteasome System (UPS)
  • NFKB1 Gene - Nuclear Factor Kappa B Subunit
  • CREBBP Gene - CREB Binding Protein
  • MMP13 Gene - Matrix Metallopeptidase 13
  • CCN2 Gene - Cellular Communication Network Factor 2 (Connective Tissue Growth Factor)
  • ELANE Gene - Elastase, Neutrophil Expressed
  • CASP3 Gene - Caspase 3 (Protein Yama)
  • COMP Gene - Cartilage Oligomeric Matrix Protein
  • GDF5 Gene - Growth Differentiation Factor 5
  • Protein Disulfide Isomerase (PDI)
  • TLL1 Gene - Tolloid Like 1
  • Pro-Lysyl Oxidase (LOX)
  • ELN Gene – Elastin
  • Integrins & Focal Adhesion Kinase (FAK)
  • SRC Gene - SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase
  • ACAN Gene – Aggrecan
  • IGF1 Gene - Insulin Like Growth Factor 1
  • ESR1 Gene - Estrogen Receptor 1
  • XYLT1 Gene - Xylosyltransferase 1
  • Glycosaminoglycan SuperPath
  • HYAL2 Gene - Hyaluronidase 2
  • Glycosaminoglycan metabolism
  • Heparan Sulfate/Heparin (HS-GAG) Metabolism
  • Chondroitin Sulfate/Dermatan Sulfate Metabolism
  • Hyaluronan Metabolism
  • Keratan Sulfate/Keratin Metabolism
  • Dermatan Sulfate Biosynthesis

Osteoarthritis Biohack

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